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> Another kind of Cataclysm, mutation gone wild
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derek_holland, Group: Heroes, Master of Mutant Creation submitted 0 Resources has rated 10 resources, submitted 0 artworks and is involved with 0 projects.

Instead of having a Final War or environmental collapse, one could simply use mutation as the Cataclysm. Say it is the result of the Chimera Curse, a sort of contagious generic modification technology that spreads by creating tiny machines within the host's skin to release exotic radiation bursts that rewrite the genomes of those within a few meters. This explains why mutations and defects are so complex and not the result of gamma radiation or the like.

If such technology escaped its controls for any reason, the Ancients would have to deal with mutant humans and uplifts who go crazy, terrified with their new condition; mutant humans and uplifts who love their new condition; pure strained humans who are terrified and hate the mutants; monstrous plants, animals, fungi, microbes, etc.; and new uplifts who have no idea what is going on.

And it spreads fast enough that engineers and researchers can not come up with a cure in time. Only those who has the GST (genetic stablization treatment) will avoid mutation for themselves and their descendants.

Cracking cities, destroying other infrastructure, covering the land is what is a constant line of succession where there are no dominate species*- that sounds cataclysmic to me.

* And what is stranger about this is those mutants that fill several niches that appear and vanish with time. They go locally extinct and then migrate in from elsewhere, thought probably not with the same appearance.
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derek_holland, Group: Heroes, Master of Mutant Creation submitted 0 Resources has rated 10 resources, submitted 0 artworks and is involved with 0 projects.

What this also means is that the biosphere turns from jungle to desert to jungle within a matter of weeks or months as predation, disease or environmentally affecting superscience pollution kills off most of the existing organisms, leaving those that are resistant or immune. They then breed and refill the physical and theoretical niches, evolving subspecies and species as needed with a boost from mutation.
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